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Cat. No.: HY-N7293

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Bakkenolide D

Name: Bakkenolide D
Brand: MedChemExpress
SKU: HY-N7293
Price: 405.00 USD
Availability: InStock
Rating: 5 (1 reviews)

고객리뷰

Based on 1 Customer Validation

Bakkenolide D is a sesquiterpene lactone. Bakkenolide D is the major component of Bakkenolides in Petasites tricholobus. Bakkenolide D exhibits anti-allergic and antihistamine activities, and can be used in studies related to allergic rhinitis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 18456-03-6
화학식: C₂₁H₂₈O₆S
분자량:408.51

보관:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (274 KB)

Bakkenolide D Chemical Structure

CAS No.: 18456-03-6

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Parmacokinetics
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Histamine Receptor Isoforms :

Parmacokinetics

Species	Dose	Route	C_max	T_max	T_1/2	AUC_0-24	AUC_inf	CL/F	V_z/F	MRT	Bioavailability
Rat^[2]	10 mg/kg	p.o.	10.1 ng/mL	15 min	11.8 h	72.1 ng·h/mL	98.3 ng·h/mL	105.2 L/h/kg	1753.3 L/kg	8.14 h	2.57 %
Rat^[2]	1 mg/kg	i.v.	191 ng/mL	5 min	8.79 h	281 ng·h/mL	309 ng·h/mL	3.67 L/h/kg	47.1 L/kg	5.17 h	/

In Vivo

Bakkenolide D exhibits low oral bioavailability in rats^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 18456-03-6
Appearance Solid
분자량 408.51
화학식 C₂₁H₂₈O₆S
SMILES

O=C(O[C@@H]1[C@]2([H])[C@@H](OC(C)=O)[C@]3(C[C@]2(C)[C@@H](C)CC1)C(OCC3=C)=O)/C=C\SC
Structure Classification
- Others
Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang FJ, et al. Anti-allergic effects of total bakkenolides from Petasites tricholobus in ovalbumin-sensitized rats. Phytother Res. 2011;25(1):116-121. [Content Brief]

[2]. Dai D, et al. LC-MS/MS determination of bakkenolide D in rats plasma and its application in pharmacokinetic studies. Biomed Chromatogr. 2013;27(9):1200-1207. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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