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Cat. No.: HY-176135

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BBDDL2204

BBDDL2204 (compound 13) is a potent and selective EZH2 covalent inhibitor. BBDDL2204 inhibits EZH2^Y641F with an IC₅₀ of 2.5 nM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₇H₄₇N₅O₅S
분자량:673.86

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

BBDDL2204 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

BBDDL2204 (compound 13) is a potent and selective EZH2 covalent inhibitor. BBDDL2204 inhibits EZH2^Y641F with an IC₅₀ of 2.5 nM^[1].

All Histone Methyltransferase Isoforms :

Chemical Information

분자량 673.86
화학식 C₃₇H₄₇N₅O₅S
SMILES

CC1=C(C=C(C=C1C(NCC2=C(C=C(NC2=O)C)SC)=O)C3=C(C=C(C=C3)CN4CCOCC4)NC(C=C)=O)N(C5CCOCC5)CC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang Y, et al. Discovery of Highly Potent and Selective EZH2 Covalent Inhibitors via Incorporating Basic Amines. J Med Chem. 2025 May 8. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

BBDDL2204

All Histone Methyltransferase Isoforms

Biological Activity

제품 설명

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BBDDL2204 Related Classifications

HY-176135 Related Classifications

Bioz

Keywords

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