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Cat. No.: HY-115663

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C620-0696

C620-0696 is an inhibitor targeting the brom domain of BPTF, with a K_D value of 35.5 μM. C620-0696 can exert cytotoxic effects on A549 and H358 cells, inhibiting the expression of c-Myc. C620-0696 inhibits cell migration and colony formation, and induces apoptosis and cell cycle arrest. C620-0696 can be used in the research of non-small cell lung cancer.

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CAS No.: 902156-98-3
화학식: C₂₄H₂₄N₄O₃
분자량:416.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

C620-0696 Chemical Structure

CAS No.: 902156-98-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All SWI/SNF Complex Isoforms :

Chemical Information

CAS No. 902156-98-3
분자량 416.47
화학식 C₂₄H₂₄N₄O₃
SMILES

O=C1C2=C(C3=C4C1=C(NCCCN(C)C)C=C(NCC5=CC=CO5)C4=NO3)C=CC=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xu J, et al. Compound C620-0696, a new potent inhibitor targeting BPTF, the chromatin-remodeling factor in non-small-cell lung cancer. Frontiers of medicine. 2020 Feb;14(1):60-7.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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C620-0696

All SWI/SNF Complex Isoforms