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Cat. No.: HY-178007

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CDK2 degrader 8

CDK2 degrader 8 (Compound1) is a CDK2 degrader. CDK2 degrader 8 shows potential anti-tumor activity by targeting CDK2. CDK2 degrader 8 can be used for the study of solid tumors (breast cancer, triple negative breast cancer, ovarian serous cystadenocarcinoma) and liquid tumors (diffuse large B-cell lymphoma, acute myelogenous leukemia) associated with abnormal CDK2 function.

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CAS No.: 3099145-52-2
화학식: C₂₅H₁₉ClF₃N₅O₅
분자량:561.90

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

CDK2 degrader 8 Chemical Structure

CAS No.: 3099145-52-2

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All CDK Isoforms :

Chemical Information

CAS No. 3099145-52-2
분자량 561.90
화학식 C₂₅H₁₉ClF₃N₅O₅
SMILES

FC(F)(OC1=CC=C(C2=NN=C(O2)NC3(CC3)C4=CC(Cl)=C5CN(C(C5=C4)=O)C6CCC(NC6=O)=O)C=C1)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. FASCHING, et al. Cyclopropyl and 1,3,4-Oxadiazole Compounds That Mediate Protein Degradation and Methods of Use Thereof. WO 2025/181261 A1. World Intellectual Property Organization (WIPO). 04 September 2025.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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CDK2 degrader 8

All CDK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CDK2 degrader 8 Related Classifications

HY-178007 Related Classifications