Cloprostenol
Based on 1 Customer Validation
Cloprostenol is a prostaglandin F-2α (PGF2α (HY-12956)) analogue. Cloprostenol induces luteolysis in marmoset monkeys. Cloprostenol can be used for the research of open-cervix pyometra.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.86%
- CAS No.: 40665-92-7
- 화학식: C22H29ClO6
- 분자량:424.92
-
보관:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
-
GPCR/G Protein Compound Library
HY-L006
-
Immunology/Inflammation Compound Library
HY-L007
-
FDA Approved & Pharmacopeial Drug Library
HY-L066
-
Angiogenesis-Related Compound Library
HY-L088
-
Membrane Protein-targeted Compound Library
HY-L149
-
Membrane Receptor-targeted Compound Library
HY-L150
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
Lactylation Compound Library
HY-L249
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Adult Female Common marmoset monkeys (250-510 g, regular ovarian cycles)[1]
-
Dosage:0.5 μg
-
Administration:i.m.; single injection
-
Result:Failed to induce luteolysis in animals treated on Days 6 or 7 of the ovarian cycle, with progesterone concentrations remaining elevated until at least Day 15-16 post-injection.
Induced luteolysis in 3/5 animals treated on Day 8.
Induced luteolysis in 1/2 animals treated on Day 9.
Induced complete, irreversible luteolysis within 24 hours in all 23 animals treated between Days 10 and 17, with progesterone falling to <10 ng/mL and remaining at this level until the day after post-treatment ovulation.
Resulted in a mean interval from injection to ovulation of 10.7 days for treatments between Days 8 and 17 where permanent luteolysis occurred, with no significant difference between mid-luteal and late luteal phase treatments, or between females paired with vasectomized versus intact males.
Produced post-treatment ovarian cycles with a normal mean length of 27.6 days and luteal phase of 18.7 days in 7 animals monitored.
-
Animal Model:Adult Female Common marmoset monkeys (range 250-510 g, pregnant between Days 19 and 43)[1]
-
Dosage:0.5 μg
-
Administration:i.m.; single injection
-
Result:Induced complete luteolysis within 24 hours in all 7 pregnant animals, with progesterone falling to <10 ng/mL and remaining at this level until the day after post-treatment ovulation.
Resulted in a mean interval from injection to ovulation of 10.9 days.
Produced 23 morphologically normal embryos out of 24 collected 6-9 days post-treatment from 11 animals, with 1 degenerate morula.
Chemical Information
-
CAS No. 40665-92-7
-
Appearance Solid
-
분자량 424.92
-
화학식 C22H29ClO6
-
Color White to off-white
-
SMILES
OC(CCC/C=C\C[C@H]1[C@@H]([C@@H](O)C[C@H]1O)/C=C/[C@H](O)COC2=CC(Cl)=CC=C2)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
순도&문서
-
Data Sheet (268 KB)
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cloprostenol Related Classifications
HY-121314 Related Classifications
Powered by Bioz