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COX-2-IN-48

COX-2-IN-48 (5-25), a COX-2 inhibitor with an IC50 of 51.7 nM for human COX-2, exerts anti-inflammatory and analgesic effects in various rodent models by inhibiting NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, the phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.

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  • 화학식: C25H17ClF3NO2
  • 분자량:455.86
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • COX-2-IN-48 Chemical Structure
    COX-2-IN-48 Chemical Structure
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Use of MCE Products

All COX Isoforms

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All NF-κB Isoforms

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All NO Synthase Isoforms

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100 mg

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  • COX-2-IN-48 Chemical Structure
    COX-2-IN-48 Chemical Structure
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  • COX-2-IN-48