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Cat. No.: HY-19612

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DDP-38003

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

DDP-38003 (Compound 15) is an orally active KDM1A/LSD1 inhibitor with an IC₅₀ value of 84 nM. DDP-38003 exhibits anticancer activity against promyelocytic leukemia.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1831167-97-5
화학식: C₂₁H₂₆N₄O
분자량:350.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DDP-38003 Chemical Structure

CAS No.: 1831167-97-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

DDP-38003 (Compound 15) is an orally active KDM1A/LSD1 inhibitor with an IC₅₀ value of 84 nM. DDP-38003 exhibits anticancer activity against promyelocytic leukemia^[1].

IC₅₀ & Target^[1]

KDM1/LSD1

84 nM (IC₅₀)

All Histone Demethylase Isoforms :

Chemical Information

CAS No. 1831167-97-5
분자량 350.46
화학식 C₂₁H₂₆N₄O
SMILES

O=C(NC1=CC=C([C@@H]2C[C@H]2N)C=C1)C(C=C3)=CC=C3N4CCN(C)CC4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Clin Exp Med

Corin: a dual inhibitor for KDM1A/HDAC1, suppresses hepatocellular carcinoma by triggering cuproptosis. [Abstract]

2025 Nov 25;26(1):33. PMID: 41286164

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vianello P, et al. Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent. J Med Chem. 2016 Feb 25;59(4):1501-17. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

DDP-38003

1 Cited Publications

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
순도&문서
References

상품명:
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DDP-38003

Publications Citing Use of MedChemExpress (MCE) DDP-38003

All Histone Demethylase Isoforms

Biological Activity

Chemical Information

Publications (1)

순도&문서

References

Calculators

Help & FAQs

DDP-38003 Related Classifications

HY-19612 Related Classifications