country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187674

Copy Link Print Information

Dicranin

Dicranin is a 15-lipoxygenase (15-LOX) inhibitor and bacterial agent. Dicranin inhibits the dioxygenation reaction of polyenoic fatty acids by irreversibly binding to lipoxygenase. Dicranin can be isolated from the phospholipids of Philonotis fontana, Leptodontium paradoxum, and Dicranum scoparium. Dicranin can be used in studies related to Gram-positive bacterial infections.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 61481-30-9
화학식: C₁₈H₂₆O₂
분자량:274.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dicranin Chemical Structure

CAS No.: 61481-30-9

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

15-LOX

All Lipoxygenase Isoforms :

In Vitro

OthersBacterial Infection

Others

Dicranin (0.36-3.6 μM) potently inhibits soybean 15-lipoxygenase, achieving 100% inhibition at 3.6 μM and 37% inhibition at 0.36 μM^[2].

Bacterial Infection

Dicranin (10-1000 μg/disc) inhibits growth of Gram-positive bacteria (Bacillus stearothermophilus, Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis) in disc diffusion assays, with the strongest activity against Streptococcus faecalis (inhibition down to 10 μg/disc), and no activity against tested Gram-negative bacteria at 1000 μg/disc^[2].
Dicranin (10-200 μg/mL; up to 24 h) acts as a bactericide against Bacillus cereus (down to 150 μg/mL) and Bacillus stearothermophilus (at 200 μg/mL), with time-dependent bactericidal/bacteriostatic effects at intermediate concentrations, weak growth inhibition against Bacillus stearothermophilus at 10 μg/mL, no activity against Bacillus cereus at 10 μg/mL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Gram Staining of Tissue Sections

Chemical Information

CAS No. 61481-30-9
분자량 274.40
화학식 C₁₈H₂₆O₂
SMILES

CC/C=C\C/C=C\C/C=C\CC#CCCCCC(O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Roy Chowdhuri S, et al. "Dicranin" in the Membrane Phospholipids of a Dicranaceae and Pottiaceae Moss Member of the Eastern Himalayan Biodiversity Hotspot. Lipids. 2018 May;53(5):539-545.

[2]. Borel C, et al. Dicranin, an antimicrobial and 15-lipoxygenase inhibitor from the moss Dicranum scoparium. Journal of natural products. 1993 Jul;56(7):1071-7.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

Dicranin

All Lipoxygenase Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Dicranin Related Classifications

HY-187674 Related Classifications

Bioz

Keywords

Your Recently Viewed Products

IC₅₀ & Target