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Cat. No.: HY-100710

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Epothilone C

Epothilone C is a polyketide natural product. Epothilone C is produced by the combined action of one nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) modules in a multienzyme system. Epothilone C can be used for tumor research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 98.53%
CAS No.: 186692-73-9
화학식: C₂₆H₃₉NO₅S
분자량:477.66

보관:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Epothilone C Chemical Structure

CAS No.: 186692-73-9

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
L929	IC₅₀	100 ng/mL Compound: 17	Compound was tested for cytotoxicity against L929 fibroblast cell lines in mouse Compound was tested for cytotoxicity against L929 fibroblast cell lines in mouse	[PMID: 9873670]
L929	IC₅₀	60 ng/mL Compound: 14	Cytotoxicity against mouse L929 cells Cytotoxicity against mouse L929 cells	[PMID: 11473410]
MCF7	IC₅₀	97 nM Compound: 3	Cytotoxicity against human MCF7 cells after 3 days by SRB assay Cytotoxicity against human MCF7 cells after 3 days by SRB assay	[PMID: 14575429]
NCI-H460	IC₅₀	280 nM Compound: 3	Cytotoxicity against human NCI-H460 cells after 3 days by SRB assay Cytotoxicity against human NCI-H460 cells after 3 days by SRB assay	[PMID: 14575429]
SF-268	IC₅₀	340 nM Compound: 3	Cytotoxicity against human SF268 cells after 3 days by SRB assay Cytotoxicity against human SF268 cells after 3 days by SRB assay	[PMID: 14575429]

Chemical Information

CAS No. 186692-73-9
Appearance Solid
분자량 477.66
화학식 C₂₆H₃₉NO₅S
SMILES

O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=CSC(C)=N2)C/C=C\CCC[C@H](C)[C@H](O)[C@@H](C)C1=O
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen H, et al. Epothilone biosynthesis: assembly of the methylthiazolylcarboxy starter unit on the EpoB subunit. Chem Biol. 2001 Sep;8(9):899-912. [Content Brief]

[2]. Mutka SC, et al. Heterologous production of epothilone C and D in Escherichia coli. Biochemistry. 2006 Jan 31;45(4):1321-30. [Content Brief]

[3]. Boddy CN, et al. Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase. J Am Chem Soc. 2003 Mar 26;125(12):3428-9. Boddy CN, et al. Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase. J Am Chem Soc. 2003 Mar 26;125(12):3428-9. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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Epothilone C

All Endogenous Metabolite Isoforms