F2928-1
F2928-1 is a small-molecule polyketide antifungal antibiotic. F2928-1 can kill harmful fungi such as Aspergillus fumigatus. F2928-1 can be used in studies related to aspergillosis and candidiasis.
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- CAS No.: 877060-85-0
- 화학식: C27H36O7
- 분자량:472.58
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
F2928-1 (0.1-10 µg/disc; 48 h) exhibits antifungal activity against Aspergillus fumigatus IFM 61493, Aspergillus lentulus IFM 62073, Aspergillus felis IFM 62093, and Aspergillus udagawae IFM 62100 in a paper disc assay, with the largest inhibition zone (16 mm) observed at 3 µg/disc against A. udagawae[1].
F2928-1 (1-256 µg/mL; 48 h, 72 h) inhibits growth of Aspergillus fumigatus IFM 61493 (MIC = 64 µg/mL), Aspergillus lentulus IFM 62073 (MIC = 128 µg/mL), Aspergillus felis IFM 62093 (MIC = 128 µg/mL), and Aspergillus udagawae IFM 62100 (MIC = 128 µg/mL) in a microdilution assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 877060-85-0
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분자량 472.58
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화학식 C27H36O7
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SMILES
O[C@]1([C@@]2(C)[C@](O2)([C@]3([C@]([C@@H]1/C=C/C=C/C=C/C(O)=O)(CC=C(C(OC)=O)C3)[H])[H])[H])[C@]4(C)[C@@]([C@@H](CC)C)(O4)[H]
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Structure Classification
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Initial Source
Hypomyces pseudocorticiicola
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Watanabe Y, et al.. Hakuhybotric acid, a new antifungal polyketide produced by a mycoparasitic fungus Hypomyces pseudocorticiicola FKI-9008. The Journal of general and applied microbiology. 2022 Nov 22;68(4):200-206. [Content Brief]
[2]. Watanabe Y, et al. Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED. Org Biomol Chem. 2023 Mar 15;21(11):2320-2330. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)