Cat. No.: HY-B0010B

Formoterol

Name: Formoterol
Brand: MedChemExpress
SKU: HY-B0010B
Price: 170.00 USD
Availability: InStock
Rating: 5 (8 reviews)

(Synonyms: (±)Formoterol)

8 Cited Publications

고객리뷰

Based on 8 publication(s) in Google Scholar

Formoterol ((±)Formoterol) is a selective β₂-adrenoceptor agonist. Formoterol is at least as β₂-adrenoceptor selective as Salbutamol (HY-B1037) and Terbutaline (HY-B0802A). Formoterol abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol can be used for the research of chronic obstructive pulmonary disease and bronchial asthma.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity : 99.55%
CAS No.: 73573-87-2
화학식: C₁₉H₂₄N₂O₄
분자량:344.40

보관:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Formoterol Chemical Structure

CAS No.: 73573-87-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-14302
Salmeterol

β2 Agonist

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
Publications (8)
용액&용해도
- In Vitro
순도&문서
References
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Adrenergic Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	0.19 nM Compound: 1	Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmunoassay Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmunoassay	[PMID: 21310610]

In Vitro

Formoterol (5-15 min intervals) potently and completely relaxes acetylcholine-pre-contracted human isolated segmental bronchi with a pEC₅₀ of 8.76^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 73573-87-2
Appearance Solid
분자량 344.40
화학식 C₁₉H₂₄N₂O₄
Color White to off-white
SMILES

O=CNC1=CC([C@H](O)CN[C@@H](C)CC2=CC=C(OC)C=C2)=CC=C1O
Synonyms

(±)Formoterol
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (8)

All In Vivo Efficacy StudyHistological Imaging/StainingRT-PCRBio/Physico-chemical Assay

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Journal Impact Factor

Nature

A two-hit mechanism triggers autoimmune hair loss. [Abstract]

2026 Oct;658(8138):1310-1318. PMID: 42816609
Nat Commun

A brain-to-liver signal mediates the inhibition of liver regeneration under chronic stress in mice. [Abstract]

2024 Nov 28;15(1):10361. PMID: 39609433

Formoterol purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Nov 28;15(1):10361. [Abstract]

The liver/body weight ratios of Formoterol fumarate (FORM, 1 mg/kg; i.p.; once daily for 21 days) +PHx mice are significantly decreased than that of Vehicle+PHx mice (n=6 mice).

Formoterol purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Nov 28;15(1):10361. [Abstract]

The mRNA expression levels of Ki67 and Pcna of Formoterol fumarate (FORM, 1 mg/kg; i.p.; once daily for 21 days) +PHx mice are significantly decreased than that of Vehicle+PHx mice (n=6 mice).
J Neuroinflammation

Hyperglycemia impairs microglia responding to retinal vasculopathy via enhanced norepinephrine-ADRB2 signaling. [Abstract]

2025 Dec 8. PMID: 41361454

Formoterol purchased from MedChemExpress. Usage Cited in: J Neuroinflammation. 2025 Dec 8. [Abstract]

Time‑lapse images depicting microglial process convergence toward vessel injury in retinas pretreated with Formoterol fumarate (2 μM; 30 min).
Inflammation

Activation of β2-Adrenergic Receptor Alleviates Viral Myocarditis by Regulating Energy Metabolism in Monocyte-derived Macrophages via the AMPK Pathway. [Abstract]

2026 Jan 15;49(1):48. PMID: 41537900

Formoterol purchased from MedChemExpress. Usage Cited in: Inflammation. 2026 Jan 15;49(1):48. [Abstract]

Representative H&E staining of the myocardium from the Vehicle, Lipo-Clod, Formoterol fumarate (0.3 mg/kg; i.p.; once a day for 2 weeks), and Formoterol fumarate + Lipo-Clod groups at 1 week and 2 weeks post-CVB3 infection (original magnification, 200× ; scale bars = 50 μm).
J Enzyme Inhib Med Chem

Natural product sennoside B disrupts liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein by inhibiting its RNA-binding activity. [Abstract]

2025 Dec;40(1):2501743. PMID: 40371698
Chem Biol Interact

Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury. [Abstract]

2025 Sep 4:111724. PMID: 40914538
Immun Inflamm Dis

Formoterol Reduces the Pro-Inflammatory Phenotype by Enhancing the Activity of Glutaminase in Monocyte-Derived Macrophages in the CVB3-Induced Viral Myocarditis. [Abstract]

2024 Nov;12(11):e70073. PMID: 39601476

Formoterol purchased from MedChemExpress. Usage Cited in: Immun Inflamm Dis. 2024 Nov;12(11):e70073. [Abstract]

Formoterol fumarate (0.3 mg/kg; i.p.; once a day for 2 weeks). Representative images of mouse hearts in each group after CVB3 infection for 1 week or 2 weeks.
Fundam Clin Pharmacol

The β2-adrenergic receptor agonist formoterol attenuates necrosis and apoptosis in the rat myocardium under experimental stress-induced cardiac injury. [Abstract]

2024 Dec;38(6):1116-1130. PMID: 38956972

용액&용해도

In Vitro:

DMSO : 100 mg/mL (290.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.9036 mL

14.5180 mL

29.0360 mL

5 mM

0.5807 mL

2.9036 mL

5.8072 mL

10 mM

0.2904 mL

1.4518 mL

2.9036 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tomioka K, et al. Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats. Arch Int Pharmacodyn Ther. 1984;267(1):91-102. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.9036 mL	14.5180 mL	29.0360 mL	72.5900 mL
	5 mM	0.5807 mL	2.9036 mL	5.8072 mL	14.5180 mL
	10 mM	0.2904 mL	1.4518 mL	2.9036 mL	7.2590 mL
	15 mM	0.1936 mL	0.9679 mL	1.9357 mL	4.8393 mL
	20 mM	0.1452 mL	0.7259 mL	1.4518 mL	3.6295 mL
	25 mM	0.1161 mL	0.5807 mL	1.1614 mL	2.9036 mL
	30 mM	0.0968 mL	0.4839 mL	0.9679 mL	2.4197 mL
	40 mM	0.0726 mL	0.3630 mL	0.7259 mL	1.8148 mL
	50 mM	0.0581 mL	0.2904 mL	0.5807 mL	1.4518 mL
	60 mM	0.0484 mL	0.2420 mL	0.4839 mL	1.2098 mL
	80 mM	0.0363 mL	0.1815 mL	0.3630 mL	0.9074 mL
	100 mM	0.0290 mL	0.1452 mL	0.2904 mL	0.7259 mL

Bioz

Keywords

Formoterol

8 Cited Publications

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Formoterol

Publications Citing Use of MedChemExpress (MCE) Formoterol

All Adrenergic Receptor Isoforms