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Cat. No.: HY-146207

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HCAIX-IN-2

HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the K_i values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively.

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CAS No.: 2389034-45-9
화학식: C₁₉H₁₆N₈O₄S
분자량:452.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

HCAIX-IN-2 Chemical Structure

CAS No.: 2389034-45-9

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the K_i values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively^[1].

IC₅₀ & Target

^[1]

CA I

2481 nM (Ki)

hCA II

456.2 nM (Ki)

hCA IX

24.6 nM (Ki)

hCA XII

45.3 nM (Ki)

All Carbonic Anhydrase Isoforms :

Chemical Information

CAS No. 2389034-45-9
분자량 452.45
화학식 C₁₉H₁₆N₈O₄S
SMILES

CC1=CC(N2C(C(N/N=C/C3=CC=NC=C3)=O)=NN(C2=N1)C4=CC=C(C=C4)S(N)(=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

HCAIX-IN-2

All Carbonic Anhydrase Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

HCAIX-IN-2 Related Classifications

HY-146207 Related Classifications

Bioz

Keywords

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