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IBI-334

고객리뷰

Based on 1 Customer Validation

IBI-334 is a bispecific B7-H3 and EGFR antibody. IBI-334 has an EGFR arm for signal blockage and is coupled with a fine-tuned B7-H3 arm with optimal affinity and binding domain. IBI-334 shows antibody-mediated cell cytotoxicity (ADCC) effects. IBI-334 has a wide range of applications in many EGFR-driven solid tumors.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 98.18%
  • 분자량:145.58 kDa
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for IBI-334
  • Experimental Validation Results for IBI-334
  • Experimental Validation Results for IBI-334
  • IBI-334 Chemical Structure
    IBI-334 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Other Forms of IBI-334:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
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All EGFR Isoforms

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100 mg

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Assay Types
  • 1/16

    Immobilized hu-B7-H3-ECD-His can bind IBI-334. The EC50 for this effect is 47.07 ng/mL.

  • 1/16

    Immobilized Human ERBB1/EGFR/HER1, His Tag can bind IBI-334. The EC50 for this effect is 56.62 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 THP-1 cells labeling B7-H3 with IBI-334 (HY-P991092, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • IBI-334 Chemical Structure
    1/16
  • IBI-334
  • Immobilized hu-B7-H3-ECD-His can bind IBI-334. The EC50 for this effect is 47.07 ng/mL.
  • Immobilized Human ERBB1/EGFR/HER1, His Tag can bind IBI-334. The EC50 for this effect is 56.62 ng/mL.
  • Flow cytometric analysis of 1X106 THP-1 cells labeling B7-H3 with IBI-334 (HY-P991092, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.