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Cat. No.: HY-129781

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L-650719

L-650719 is a topical carbonic anhydrase inhibitor (CAI) with a K_i of 10 nM for CA II. L-650719 has shown good intraocular pressure-lowering effects in a rabbit model. L-650719 may be used in glaucoma research.

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CAS No.: 96803-89-3
화학식: C₈H₇NO₃S₂
분자량:229.28

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

L-650719 Chemical Structure

CAS No.: 96803-89-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

CA Ⅱ

10 nM (Ki)

All Carbonic Anhydrase Isoforms :

Chemical Information

CAS No. 96803-89-3
분자량 229.28
화학식 C₈H₇NO₃S₂
SMILES

O=S(C1=CC2=CC=C(O)C=C2S1)(N)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bar-Ilan A, Pessah NI, Maren TH. Ocular hypotensive activity and disposition of the topical carbonic anhydrase inhibitor 6-hydroxy-benzo[b]thiophene-2-sulfonamide, L-650,719, in the rabbit. J Ocul Pharmacol. 1989 Summer;5(2):99-110. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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상품명:
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L-650719

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

L-650719 Related Classifications

HY-129781 Related Classifications