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Cat. No.: HY-129289

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NSC 13987

NSC 13987 is a Nef site I inhibitor. NSC 13987 binds to Nef site I and disrupts the Nef-calnexin interaction. NSC 13987 restores cholesterol efflux inhibited by Nef. NSC 13987 is applicable to the research of HIV-associated atherosclerosis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 81-94-7
화학식: C₃₁H₁₇NO₃
분자량:451.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

NSC 13987 Chemical Structure

CAS No.: 81-94-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
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Classifications
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Biological Activity

제품 설명

IC₅₀ & Target^[1]

HIV-1 Nef

All HIV Isoforms :

Chemical Information

CAS No. 81-94-7
분자량 451.47
화학식 C₃₁H₁₇NO₃
SMILES

O=C1C2=C(C(C3=CC=CC(NC(C=CC4=C56)=C6C=CC=C5C(C7=CC=CC=C74)=O)=C13)=O)C=CC=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Adzhubei AA, et al. Modelling interaction between HIV-1 Nef and calnexin. AIDS. 2018;32(15):2103-2111. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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NSC 13987

All HIV Isoforms