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Cat. No.: HY-N20723

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Ovalichromene B

Ovalichromene B is a flavonone and phytochemical with an IC₅₀ of 78.83 ± 1.04 μM, found in the dry stem of Pongamia pinnata (L.) Pierre.Ovalichromene B inhibits lipopolysaccharide-induced nitric oxide production.Ovalichromene B exhibits high intestinal absorption, non-mutagenicity, non-hepatotoxicity, and no predicted hERG I or II channel inhibition.Ovalichromene B can be used for the research of neurodegenerative diseases.Ovalichromene B can be used for the research of carbapenem-resistant enterobacterales infections.

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CAS No.: 62868-06-8
화학식: C₂₁H₁₈O₅
분자량:350.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ovalichromene B Chemical Structure

CAS No.: 62868-06-8

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

Ovalichromene B is a flavonone and phytochemical with an IC₅₀ of 78.83 ± 1.04 μM, found in the dry stem of Pongamia pinnata (L.) Pierre^[1].Ovalichromene B inhibits lipopolysaccharide-induced nitric oxide production^[1].Ovalichromene B exhibits high intestinal absorption, non-mutagenicity, non-hepatotoxicity, and no predicted hERG I or II channel inhibition^[2].Ovalichromene B can be used for the research of neurodegenerative diseases^[1].Ovalichromene B can be used for the research of carbapenem-resistant enterobacterales infections^[2].

All NO Synthase Isoforms :

In Vitro

Ovalichromene B (0.1-100 μM) weakly inhibits LPS-induced nitric oxide production in BV-2 microglial cells with an IC₅₀ of 78.83 μM and shows no cytotoxicity at concentrations up to 100 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 62868-06-8
분자량 350.37
화학식 C₂₁H₁₈O₅
SMILES

O=C1C2=C(C3=C(C=C2)OC(C)(C)C=C3)O[C@@H](C1)C=4C=C5C(=CC4)OCO5
Structure Classification
- Flavonoids
- Other Flavonoids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Li J, et al. Natural therapeutic agents for neurodegenerative diseases from a traditional herbal medicine Pongamia pinnata (L.) Pierre. Bioorganic & medicinal chemistry letters. 2015 Jan 01;25(1):53-8. [Content Brief]

[2]. Jangid H, et al. Structure-Based Identification of Ponganone V from Pongamia pinnata as a Potential KPC-2 β-Lactamase Inhibitor: Insights from Docking, ADMET, and Molecular Dynamics. Microbiology Research. 2025;16(12):262.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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Ovalichromene B

All NO Synthase Isoforms