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Cat. No.: HY-N9353

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Pabulenol

Pabulenol is a linear furanocoumarin derivative with anti-proliferative, cytotoxic and anti-platelet aggregation activities. Pabulenol inhibits the proliferation of lymphoma cells and platelet aggregation. Pabulenol can be used in relevant studies on T-cell lymphoma, hypertension and thrombotic diseases such as atherosclerosis.

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CAS No.: 33889-70-2
화학식: C₁₆H₁₄O₅
분자량:286.28

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pabulenol Chemical Structure

CAS No.: 33889-70-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Pabulenol (72 h) inhibits proliferation of L5178Y PAR and L5178Y MDR mouse T-cell lymphoma cells with IC₅₀ values of 30.47 μM and 29.28 μM, respectively, after 72 h of incubation^[1].
Pabulenol (24 h) induces cytotoxicity in L5178Y PAR mouse T-cell lymphoma cells and NIH/3T3 mouse embryonic fibroblast cells with IC₅₀ values of 51.32 μM and 54.09 μM, respectively^[1].
Pabulenol (2-20 μM; 10 min) does not inhibit the ABCB1 efflux pump in L5178Y MDR mouse T-cell lymphoma cells, as shown by FAR values of 0.82 and 0.75, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 33889-70-2
분자량 286.28
화학식 C₁₆H₁₄O₅
SMILES

O(C[C@H](C(C)=C)O)C=1C2=C(C=C3C1C=CO3)OC(=O)C=C2
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Plants
- Umbelliferae
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Mottaghipisheh J, et al.. Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia. Pharmaceutical biology. 2018 Dec;56(1):658-664. [Content Brief]

[2]. Lee YY, et al.. Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas. Archives of pharmacal research. 2003 Sep;26(9):723-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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