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Cat. No.: HY-120053

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SC-53606

SC-53606 is a potent and selective 5-HT₄ receptor antagonist, with a pA2 value of 8.13. SC-53606 acts as an antagonist of 5-HT₄ receptor-mediated relaxation of Carbachol (HY-B1208)-induced contractions.

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CAS No.: 151898-33-8
화학식: C₁₆H₁₉ClN₄O
분자량:318.80

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

SC-53606 Chemical Structure

CAS No.: 151898-33-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]^[2]

5-HT₄ Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 151898-33-8
분자량 318.80
화학식 C₁₆H₁₉ClN₄O
SMILES

O=C(NC[C@H]1[C@@]2(CCCN2CC1)[H])C3=CC(Cl)=CN4C3=NC=C4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang DC, et al. SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae. J Pharmacol Exp Ther. 1993 Sep;266(3):1339-47. [Content Brief]

[2]. Becker D P, et al. Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype. Pharmacochemistry Library. Elsevier, 1996, 24: 99-120.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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상품명:
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SC-53606

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

SC-53606 Related Classifications

HY-120053 Related Classifications