Schinlignan B
Schinlignan B (Angeloylgomisin P) is a lignan with antioxidant, anti-HIV, anti-HBV activities, which is found in plants of the Schisandra genus. Schinlignan B is promising for research of antioxidant-associated diseases.
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- CAS No.: 77881-08-4
- 화학식: C28H34O9
- 분자량:514.56
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
55.1 μM
Compound: Gomisin B
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
| DU-145 | IC50 |
64.7 μM
Compound: Gomisin B
|
Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
| HEK293 | IC50 |
52 μM
Compound: Gomisin B
|
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
| IMR-32 | IC50 |
66.8 μM
Compound: Gomisin B
|
Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
| MDA-MB-231 | IC50 |
60.5 μM
Compound: Gomisin B
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
| PANC-1 | IC50 |
53.6 μM
Compound: Gomisin B
|
Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
| SiHa | IC50 |
51.2 μM
Compound: Gomisin B
|
Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
|
[PMID: 28818768] |
Chemical Information
-
CAS No. 77881-08-4
-
분자량 514.56
-
화학식 C28H34O9
-
SMILES
C[C@H]1CC(C=C(OCO2)C2=C3OC)=C3C4=C(OC)C(OC)=C(OC)C=C4[C@H](OC(/C(C)=C\C)=O)[C@@]1(O)C
-
Synonyms
Angeloylgomisin P
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)