Trehalulose
Trehalulose is a microbial metabolite and a beneficial structural isomer of Sucrose (HY-B1779). Trehalulose attenuates blood glucose and insulin response. Trehalulose exhibits antioxidant activity to support oxidative stability. Trehalulose can be used for food and beverage applications, and can be used for the research of dental caries, diabetes, obesity.
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- CAS No.: 51411-23-5
- 화학식: C12H22O11
- 분자량:342.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
제품 설명
IC50 & Target
[1]|
Microbial Metabolite |
In Vitro
Trehalulose (1.25-5 %) activates human epidermal fibroblast cells and reduces UV-induced oxidative stress[1].
Trehalulose (1%) minimally inhibits the activity of α-glucosyltransferase from Pseudomonas mesoacidophila MX-45, reducing relative activity to 98% of the control[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rats[1]
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Dosage:1.47 g/kg bw
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Administration:p.o.; daily; 26 weeks
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Result:Was hydrolyzed into glucose and fructose by the sucrase-isomaltase complex in the rat intestinal system.
Showed efficient digestibility.
Caused no significant side effects such as diarrhea even after prolonged intake for 26 weeks.
Chemical Information
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CAS No. 51411-23-5
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분자량 342.30
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화학식 C12H22O11
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SMILES
O(CC([C@H]([C@@H]([C@@H](CO)O)O)O)=O)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
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Structure Classification
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Initial Source
Pseudomonas mesoacidophila MX-45
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Seevanathan Y, et al. Trehalulose: Exploring its benefits, biosynthesis, and enhanced production techniques. Carbohydr Res. 2024;545:109293. [Content Brief]
[2]. Nagai Y, et al. Characterization of alpha-glucosyltransferase from Pseudomonas mesoacidophila MX-45. Biosci Biotechnol Biochem. 1994;58(10):1789-1793. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Trehalulose Related Classifications
HY-133202 Related Classifications
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Keywords
- Trehalulose
- 51411-23-5
- Endogenous Metabolite
- α-glucosidase
- Pseudomonas mesoacidophila MX-45
- recombinant trehalose synthase (TreM)
- human epidermal fibroblast cells
- Metschnikowia reukaufii
- amylosucrase-type enzyme (DdAS)
- Deinococcus deserti
- Blastobotrys adeninivorans
- oral streptococci glucosyltransferases
- Maltase (BaAG2)
- Inhibitor
- inhibitor
- inhibit