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Art. -Nr.: HY-183054

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KRAS-IN-66

KRAS-IN-66 is a KRAS inhibitor with in vitro inhibitory activity against KRAS G12D/G12V. KRAS-IN-66 can be used in research related to KRAS G12D/G12V mutant tumors.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3056973-74-8
Formel: C₂₈H₃₃FN₁₀OS₂
Molecular Weight:608.76

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

KRAS-IN-66 Chemical Structure

CAS. Nr.: 3056973-74-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

KRAS-IN-66 is a KRAS inhibitor with in vitro inhibitory activity against KRAS G12D/G12V. KRAS-IN-66 can be used in research related to KRAS G12D/G12V mutant tumors^[1].

IC₅₀ & Target

^[1]

KRas G12D

KRas G12V

Alle Ras Isoform-spezifische Produkte anzeigen :

In Vitro

KRAS-IN-66 (Compound 115) exhibits potent inhibitory activity against KRAS G12D and KRAS G12V (IC₅₀ < 0.01 μM)^[1].
KRAS-IN-66 can be resolved into 2 chiral isomers (120A and 120B)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3056973-74-8
Molecular Weight 608.76
Formel C₂₈H₃₃FN₁₀OS₂
SMILES

N#CC1=C(N)SC2=C1C3(SC2)CN(C4=NC(OC[C@@]56N(CCC6)C[C@@H](C5)F)=NC(N(C)C(C7=C(N=CC=C7)N)C)=N4)C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Lin H. Combination therapies with kras modulators. WO2026060384A1, 2026.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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KRAS-IN-66

Alle Ras Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

KRAS-IN-66 Related Classifications

HY-183054 Related Classifications

Bioz

Keywords

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