KRAS ligand 6
KRAS ligand 6 (Compound 37) is a KRAS ligand. KRAS ligand 6 can be used as a Ligand for Target Protein for PROTAC to synthesize KRAS PROTAC degraders, such as RP04340 (HY-189222). KRAS ligand 6 can be used for research on KRAS-driven cancers, including pancreatic ductal adenocarcinoma, colorectal cancer, and lung adenocarcinoma.
For research use only. We do not sell to patients.
- Formula: C31H30F4N4O4
- Molecular Weight:598.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
K-RAS |
Chemical Information
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Molecular Weight 598.59
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Formula C31H30F4N4O4
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SMILES
OC[C@]1(COC2=NC(N(CCC3)C[C@]43CCO4)=C(C=NC(C5=C6C(CC)=C(F)C=CC6=CC(O)=C5)=C7F)C7=N2)C(F)(F)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)