L-Leucine-2-13C,15N
Based on 1 Customer Validation
L-Leucine-2-13C,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 285977-88-0
- Formula: C513CH1315NO2
- Molecular Weight:133.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 285977-88-0
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Unlabeled Cas 61-90-5
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Appearance Solid
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Molecular Weight 133.16
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Formula C513CH1315NO2
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Color White to off-white
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SMILES
CC(C)C[13C@H]([15NH2])C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 25 mg/mL (187.74 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.5098 mL | 37.5488 mL | 75.0976 mL | 187.7441 mL |
| 5 mM | 1.5020 mL | 7.5098 mL | 15.0195 mL | 37.5488 mL | |
| 10 mM | 0.7510 mL | 3.7549 mL | 7.5098 mL | 18.7744 mL | |
| 15 mM | 0.5007 mL | 2.5033 mL | 5.0065 mL | 12.5163 mL | |
| 20 mM | 0.3755 mL | 1.8774 mL | 3.7549 mL | 9.3872 mL | |
| 25 mM | 0.3004 mL | 1.5020 mL | 3.0039 mL | 7.5098 mL | |
| 30 mM | 0.2503 mL | 1.2516 mL | 2.5033 mL | 6.2581 mL | |
| 40 mM | 0.1877 mL | 0.9387 mL | 1.8774 mL | 4.6936 mL | |
| 50 mM | 0.1502 mL | 0.7510 mL | 1.5020 mL | 3.7549 mL | |
| 60 mM | 0.1252 mL | 0.6258 mL | 1.2516 mL | 3.1291 mL | |
| 80 mM | 0.0939 mL | 0.4694 mL | 0.9387 mL | 2.3468 mL | |
| 100 mM | 0.0751 mL | 0.3755 mL | 0.7510 mL | 1.8774 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.