2. Protein Tyrosine Kinase/RTK
  3. Src
  4. LCB 03-0110

LCB 03-0110, a thienopyridine derivative, is a potent pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor. LCB 03-0110 suppresses scar formation by inhibiting fibroblast and macrophage activation.

For research use only. We do not sell to patients.

LCB 03-0110 Chemical Structure

LCB 03-0110 Chemical Structure

CAS No. : 1228102-01-9

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Based on 1 publication(s) in Google Scholar

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Description

LCB 03-0110, a thienopyridine derivative, is a potent pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor. LCB 03-0110 suppresses scar formation by inhibiting fibroblast and macrophage activation[1].

In Vitro

LCB 03-0110 suppresses the proliferation and migration of primary dermal fibroblasts induced by transforming growth factor β1 and type I collagen[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LCB 03-0110 Related Antibodies
In Vivo

LCB 03-0110 suppresses the accumulation of myofibroblast and macrophage cells in the healing wound and reduced hypertrophic scar formation after wound closing on rabbit ears[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

417.52

Formula

C24H23N3O2S
CAS No.
SMILES

OC1=CC=CC(NC2=C3SC(C4=CC(CN5CCOCC5)=CC=C4)=CC3=NC=C2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LCB 03-0110 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LCB 03-01101228102-01-9SrcInhibitorinhibitorinhibit

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LCB 03-0110
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HY-110367A
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