2. Membrane Transporter/Ion Channel
    Neuronal Signaling
    GPCR/G Protein
  3. Calcium Channel
    5-HT Receptor
  4. Levemopamil hydrochloride

Levemopamil hydrochloride 

Cat. No.: HY-113643
Handling Instructions

Levemopamil hydrochloride is a blood-brain barrier penetrable calcium channel blocker and a 5-HT2 antagonist. Levemopamil hydrochloride can be used for temporary occlusion and neurological disease research.

For research use only. We do not sell to patients.

Levemopamil hydrochloride Chemical Structure

Levemopamil hydrochloride Chemical Structure

CAS No. : 101238-54-4

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Description

Levemopamil hydrochloride is a blood-brain barrier penetrable calcium channel blocker and a 5-HT2 antagonist. Levemopamil hydrochloride can be used for temporary occlusion and neurological disease research[1].

In Vivo

Levemopamil hydrochloride (30 mg/kg; i.p., once) regulates bilateral damping of carotid arteries (BCCA) process and reduces spatial memory deficits induced by cerebral oligemia of rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Han-Wistar rats with bilateral damping of carotid arteries (BCCA)[1]
Dosage: 30 mg/kg
Administration: Intraperitoneal injection; 30 mg/kg, once
Result: Showed no effect on GABA or ACh content in either BCCA or sham-operated control rats. Significantly increased swimming speed of BCCA rats in swimming test. Prevented the increasing of escape latency to reach the hidden platform.
Molecular Weight

370.96

Formula

C23H31ClN2
CAS No.
SMILES

CN(CCC1=CC=CC=C1)CCC[[email protected]@](C#N)(C2=CC=CC=C2)C(C)C.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

Levemopamil101238-54-4Calcium Channel5-HT ReceptorCa2+ channelsCa channelsSerotonin Receptor5-hydroxytryptamine Receptorblood-brain barriertemporary occlusionneurological diseaseBCCAmemory deficitsInhibitorinhibitorinhibit

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