Hydroxy Fatty Acids

2,3-Dinor thromboxane B2 (2,3-Dinor-TXB2), a metabolite of urine, serves as an indicator of the production of thromboxane A2 (TxA2) in the body, and can be used as a tool to study the role of thromboxane in various pathophysiological processes in the human body.

PGD2 ethanolamide is the COX-2 dependent metabolite of Anandamide that induces apoptosis in colorectal carcinoma (CRC) cells.

5,7-Dihydroxy-11-ketotetranorprostanoic acid is a urinary metabolite of prostaglandin F_2α and precursor to tetranor-PGF metabolites, exhibits hardly activity in blood pressure assay and smooth muscle stiumulation assay.

Prostaglandin E1 alcohol (compound 89) is a prostaglandin analog.

17R-HETE is an arachidonic acid metabolite through cytochrome P-450 pathways. 17R-HETE exhibits efficacy in inducing cardic hypertrophy with less efficiency with compared to 17S-HETE.

3-Hydroxyoctadecanoyl-CoA is a metabolite of lipid metabolism.

(5S,6R)-DiHETE is an enantiomer of (5,6)-DiHETEs. (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC₅₀ of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists.

Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin E1 (HY-B0131). Prostaglandin E1 is a prostanoid receptor ligand.

Acetoacetyl CoA is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA from two acetyl-CoA molecules. Acetoacetyl CoA is essential for cholesterol biosynthesis. Acetoacetyl-CoA is also a intermediate in the biological breakdown and synthesis of fatty acids.

6-O-Staroyl-L-ascorbic acid is an organic compound commonly used in cosmetics and skin care products. It can be used as an antioxidant and whitening agent, and is widely used in anti-aging, moisturizing and skin repairing. In addition, this compound is used as a catalyst or buffer in certain chemical reactions.

(R,Z)-12-hydroxyoctadec-9-enoic acid, sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Isobutyryl coenzyme A (Isobutyryl CoA) lithium is A coenzyme A involved in the metabolic pathway of fatty acids. Isobutyryl coenzyme A lithium is made by combining isobutyric acid (short chain branched fatty acid) with coenzyme A.

2-Hydroxydodecanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

11,12-DiHETrE is a dihydroxy fatty acid metabolite of Arachidonic Acid (HY-109590). 11,12-DiHETrE is converted to 11,12-DiHETrE under elevated soluble epoxide hydrolase (sEH) activity, a process closely related to inflammation and oxidative stress. 11,12-DiHETrE can serve as a single biomarker to differentiate between NAFL (non-alcoholic fatty liver disease) and NASH (non-alcoholic steatohepatitis). 11,12-DiHETrE can be used in studies on preterm birth, autism, and pulmonary hypertension.

Malonyl CoA is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA is also a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1.

20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome.

6-trans-12-epi-Leukotriene B4, an arachidonic acid metabolite, is a potent anti-inflammatory agent.

6-trans-leukotriene B4 is a neutrophil chemotaxin in the guinea pig dermis.

11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum.

Tetranor-PGDM is an abundant urinary metabolite reflects biosynthesis of prostaglandin D₂.