Copy Link Print Information

LM-299

LM-299 is a bispecific antibody targeting PD-1 and VEGF with anti-tumor activity. The dual binding activity of LM-299 is achieved through the effective binding of its Fab-terminal anti-VEGF-A antibody to human VEGF-A, as well as the blocking effect of its Fc-terminal anti-PD-1 antibody on the PD-1/PD-L1 pathway. LM-299 binds to and modulates PD-1 and VEGF. LM-299 can be used in studies related to advanced malignant tumors, advanced solid tumors, and advanced non-small cell lung cancer.

For research use only. We do not sell to patients.

  • Purity: 95.78%
  • Molecular Weight:175.49 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for LM-299
  • Experimental Validation Results for LM-299
  • Experimental Validation Results for LM-299
  • LM-299 Chemical Structure
    LM-299 Chemical Structure
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
LM-299 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

All VEGFR Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Tetravalent IgG-VHH

  • 1/16

    Immobilized Human PD-1 Protein, His Tag can bind LM-299. The EC50 for this effect is 164.3 ng/mL.

  • 1/16

    Immobilized Human VEGF165 Protein,hFc Tag can bind LM-299. The EC50 for this effect is 77.9 ng/mL.

  • LM-299 Chemical Structure
    1/16
  • LM-299
  • Immobilized Human PD-1 Protein, His Tag can bind LM-299. The EC50 for this effect is 164.3 ng/mL.
  • Immobilized Human VEGF165 Protein,hFc Tag can bind LM-299. The EC50 for this effect is 77.9 ng/mL.
  • Tetravalent IgG-VHH