1. NF-κB Metabolic Enzyme/Protease Autophagy Apoptosis
  2. Autophagy Keap1-Nrf2 Endogenous Metabolite Apoptosis
  3. Luteolin monohydrate

Luteolin (monohydrate) is the monohydrate of Luteolin. Luteolin (Luteoline), a flavonoid, is also a potent Nrf2 inhibitor. Luteolin has anti-inflammatory and anticancer properties, induces apoptosis and cell cycle arrest in multiple human cancer cell lines, including non-small lung cancer cells, and inhibits cell metastasis and angiogenesis.

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CAS No. : 6113-16-2

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Based on 89 publication(s) in Google Scholar

Other Forms of Luteolin monohydrate:

Top Publications Citing Use of Products

89 Publications Citing Use of MCE Luteolin monohydrate

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Bio/Physico-chemical Assay
Histological Imaging/Staining
Cell Proliferation/Viability Assay
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    Luteolin monohydrate purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Oct 7;16(1):714.  [Abstract]

    Luteolin (10 mg/kg; p.o.; daily for 4 weeks). Biochemical analysis of blood in NC, luteolin, B[a]P and B[a]P + luteolin groups.

    Luteolin monohydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Oct:146:157117.  [Abstract]

    Luteolin (0-100 μM; 48 h). Cell viability of MC38 and CT26 cells treated with varying concentrations of luteolin is assessed using the CCK-8 assay.

    Luteolin monohydrate purchased from MedChemExpress. Usage Cited in: Theranostics. 2024 Sep 3;14(14):5551-5570.  [Abstract]

    Luteolin (25 mg/kg, i.p., daily). Immunofluorescence analysis of astrocytes co-stained with NRF2 in the CA1 region of mice across different groups. Treatment with Luteolin, an NRF2 inhibitor, results in a reduction of NRF2 expression.

    Luteolin monohydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2024 May 10:130:155611.  [Abstract]

    Luteolin (60-120 μM; injected into the basal ganglia of the mice using a microsyringe; a total injection time of no less than 5 min). Hematoxylin and eosin staining of intracranial tumor plantation shows the tumor size in the coronal location of four groups.

    Luteolin monohydrate purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Jun 13:9:620.  [Abstract]

    Effects of Luteolin on the level of CTSD and p-CDK2 in HK-2 cells. The western blotting results of CTSD and p-CDK2 in the NaOx-stimulated HK-2 cells treated by Luteolin.

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    Description

    Luteolin (monohydrate) is the monohydrate of Luteolin. Luteolin (Luteoline), a flavonoid, is also a potent Nrf2 inhibitor. Luteolin has anti-inflammatory and anticancer properties, induces apoptosis and cell cycle arrest in multiple human cancer cell lines, including non-small lung cancer cells, and inhibits cell metastasis and angiogenesis[1].

    Clinical Trial
    Molecular Weight

    304.25

    Formula

    C15H12O7

    CAS No.
    Appearance

    Solid

    Color

    Light yellow to yellow

    SMILES

    O=C1C=C(C2=CC(O)=C(O)C=C2)OC3=C1C(O)=CC(O)=C3.O

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Purity & Documentation

    Purity: 99.13%

    References
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Luteolin monohydrate
    Cat. No.:
    HY-W303895
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