LY-510929
LY-510929 is a compound that induces left ventricular hypertrophy (LVH). Related studies have identified the relevant conditions in which LY-510929 may induce LVH by measuring multiple markers and using multiple techniques.
For research use only. We do not sell to patients.
- CAS No.: 401789-93-3
- Formula: C26H25NO5S
- Molecular Weight:463.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CV-1 | EC50 |
0.004 μM
Compound: 7
|
Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
|
10.1007/s00044-012-0003-4 |
| CV-1 | EC50 |
0.009 μM
Compound: 7
|
Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
|
10.1007/s00044-012-0003-4 |
| CV-1 | EC50 |
4 nM
Compound: 2
|
Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cells
Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cells
|
[PMID: 15115385] |
| CV-1 | EC50 |
9 nM
Compound: 2
|
Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cells
Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cells
|
[PMID: 15115385] |
Chemical Information
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CAS No. 401789-93-3
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Molecular Weight 463.55
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Formula C26H25NO5S
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SMILES
CC(OC(C1=CC=CS1)=N2)=C2CCOC3=CC=C(C=C3)C[C@@](C)(C(O)=O)OC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)