Metanephrine
Based on 1 Customer Validation
Metanephrine is the O-methylated metabolite of epinephrine that can be used for the research of diagnosis of pheochromocytoma.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 5001-33-2
- Formula: C10H15NO3
- Molecular Weight:197.23
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Metabolism/Protease Compound Library
HY-L012
-
Natural Product Library
HY-L021
-
Anti-Cancer Compound Library
HY-L025
-
Human Endogenous Metabolite Compound Library
HY-L030
-
Phenols Library
HY-L057
-
Alkaloids Library
HY-L071
-
Food-Sourced Compound Library
HY-L094
-
Anti-Cancer Natural Product Library
HY-L107
-
Human Metabolite Library
HY-L123
-
Coagulation and Anti-coagulation Compound Library
HY-L136
-
Animal-Sourced Natural Product Library
HY-L157
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Natural Product Library Plus
HY-L021P
-
Natural Product and Natural Product-Like Compound Library
HY-L021M
-
Bioactive Compound Library
HY-L001
-
RO5 Drug-like Natural Product Library
HY-L200
-
High-Throughput Bioactive Compound Library
HY-L205
-
High-Throughput Natural Product Library
HY-L206
-
Mass Spectrometry Human Endogenous Metabolite Library
HY-L207
-
Mass Spectrometry Human Metabolite Library
HY-L215
-
Mass Spectrometry Natural Product Library
HY-L262
All Endogenous Metabolite Isoforms
More
Biological Activity
|
Human Endogenous Metabolite |
Metanephrine inhibits MPP+ uptake into Caki-1 cells and rat hepatocytes with IC50s of 34.2 µM and 302.0 µM, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 5001-33-2
-
Appearance Solid
-
Molecular Weight 197.23
-
Formula C10H15NO3
-
Color White to off-white
-
SMILES
OC(CNC)C1=CC=C(O)C(OC)=C1
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (101.40 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Eisenhofer G, et al. Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. Clin Chem. 2011 Mar;57(3):411-20. [Content Brief]
[2]. Martel F, et al. Comparison between uptake2 and rOCT1: effects of catecholamines, metanephrines and corticosterone. Naunyn Schmiedebergs Arch Pharmacol. 1999 Apr;359(4):303-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0702 mL | 25.3511 mL | 50.7022 mL | 126.7556 mL |
| 5 mM | 1.0140 mL | 5.0702 mL | 10.1404 mL | 25.3511 mL | |
| 10 mM | 0.5070 mL | 2.5351 mL | 5.0702 mL | 12.6756 mL | |
| 15 mM | 0.3380 mL | 1.6901 mL | 3.3801 mL | 8.4504 mL | |
| 20 mM | 0.2535 mL | 1.2676 mL | 2.5351 mL | 6.3378 mL | |
| 25 mM | 0.2028 mL | 1.0140 mL | 2.0281 mL | 5.0702 mL | |
| 30 mM | 0.1690 mL | 0.8450 mL | 1.6901 mL | 4.2252 mL | |
| 40 mM | 0.1268 mL | 0.6338 mL | 1.2676 mL | 3.1689 mL | |
| 50 mM | 0.1014 mL | 0.5070 mL | 1.0140 mL | 2.5351 mL | |
| 60 mM | 0.0845 mL | 0.4225 mL | 0.8450 mL | 2.1126 mL | |
| 80 mM | 0.0634 mL | 0.3169 mL | 0.6338 mL | 1.5844 mL | |
| 100 mM | 0.0507 mL | 0.2535 mL | 0.5070 mL | 1.2676 mL |
Metanephrine Related Classifications
HY-113299 Related Classifications
Powered by Bioz