2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Metanephrine

Metanephrine is the O-methylated metabolite of epinephrine that can be used for the research of diagnosis of pheochromocytoma.

For research use only. We do not sell to patients.

Metanephrine Chemical Structure

Metanephrine Chemical Structure

CAS No. : 5001-33-2

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10 mg USD 95 In-stock
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Based on 1 publication(s) in Google Scholar

Metanephrine Related Antibodies

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Description

Metanephrine is the O-methylated metabolite of epinephrine that can be used for the research of diagnosis of pheochromocytoma[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Metanephrine inhibits MPP+ uptake into Caki-1 cells and rat hepatocytes with IC50s of 34.2 µM and 302.0 µM, respectively[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Metanephrine Related Antibodies
Clinical Trial
Molecular Weight

197.23

Formula

C10H15NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(CNC)C1=CC=C(O)C(OC)=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (633.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0702 mL 25.3511 mL 50.7022 mL
5 mM 1.0140 mL 5.0702 mL 10.1404 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.0702 mL 25.3511 mL 50.7022 mL 126.7556 mL
5 mM 1.0140 mL 5.0702 mL 10.1404 mL 25.3511 mL
10 mM 0.5070 mL 2.5351 mL 5.0702 mL 12.6756 mL
15 mM 0.3380 mL 1.6901 mL 3.3801 mL 8.4504 mL
20 mM 0.2535 mL 1.2676 mL 2.5351 mL 6.3378 mL
25 mM 0.2028 mL 1.0140 mL 2.0281 mL 5.0702 mL
30 mM 0.1690 mL 0.8450 mL 1.6901 mL 4.2252 mL
40 mM 0.1268 mL 0.6338 mL 1.2676 mL 3.1689 mL
50 mM 0.1014 mL 0.5070 mL 1.0140 mL 2.5351 mL
60 mM 0.0845 mL 0.4225 mL 0.8450 mL 2.1126 mL
80 mM 0.0634 mL 0.3169 mL 0.6338 mL 1.5844 mL
100 mM 0.0507 mL 0.2535 mL 0.5070 mL 1.2676 mL
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Metanephrine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metanephrine5001-33-2Endogenous MetaboliteInhibitorinhibitorinhibit

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