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製品番号: HY-N21666

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Micranoic acid B

Micranoic acid B is a terpenoid compound. Micranoic acid B exhibits cytotoxicity against cancer cells and shows comparable activity against multidrug-resistant and parental cancer cell lines. Micranoic acid B can be used for research on lung cancer, prostate cancer, and nasopharyngeal epidermoid carcinoma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 659738-09-7
分子式: C₂₂H₃₂O₃
分子量:344.50

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (288 KB)

Micranoic acid B 構造式

CAS 番号: 659738-09-7

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Micranoic acid B is a terpenoid compound. Micranoic acid B exhibits cytotoxicity against cancer cells and shows comparable activity against multidrug-resistant and parental cancer cell lines. Micranoic acid B can be used for research on lung cancer, prostate cancer, and nasopharyngeal epidermoid carcinoma^[1]^[2]^[3]^[4]^[5]^[6]^[7].

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	GI50	12.79 μM	Cytotoxicity against human lung carcinoma A549 cells assessed as 50% inhibition of cell growth incubated for 72 hrs by sulforhodamine B (SRB) colorimetric assay. Cytotoxicity against human lung carcinoma A549 cells assessed as 50% inhibition of cell growth incubated for 72 hrs by sulforhodamine B (SRB) colorimetric assay.	23883077
PC-3	GI50	11.83 μM	Cytotoxicity against human prostate carcinoma PC-3 cells assessed as 50% inhibition of cell growth incubated for 72 hrs by sulforhodamine B (SRB) colorimetric assay. Cytotoxicity against human prostate carcinoma PC-3 cells assessed as 50% inhibition of cell growth incubated for 72 hrs by sulforhodamine B (SRB) colorimetric assay.	23883077
KB	GI50	12.62 μM	Cytotoxicity against human epidermoid carcinoma of the nasopharynx KB cells assessed as 50% inhibition of cell growth incubated for 72 hrs by sulforhodamine B (SRB) colorimetric assay. Cytotoxicity against human epidermoid carcinoma of the nasopharynx KB cells assessed as 50% inhibition of cell growth incubated for 72 hrs by sulforhodamine B (SRB) colorimetric assay.	23883077

体外実験

Anti-cancerOthers

Anti-cancer

Micranoic acid B (compound 5) (72 h) exhibits moderate cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines with GI₅₀ values of 11.83-12.79 μM^[4].

Others

Micranoic acid B (compound 93) is a norcycloartane triterpenoid isolated from Schisandra micrantha that features an octanortriterpenoid backbone lacking the entire C-17 side chain^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 659738-09-7
分子量 344.50
分子式 C₂₂H₃₂O₃
SMILES

C(CC(O)=O)[C@]12[C@]3([C@]([C@@]4(C)[C@](C)(CC3)C(=O)CC4)(CC[C@H]1C(C)=C)[H])C2
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (288 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Rao G, et al. α-Glucosidase and Bacterial β-Glucuronidase Inhibitors from the Stems of Schisandra sphaerandra Staph. Pharmaceuticals (Basel). 2022 Mar 9;15(3):329.

[2]. Xiao WL, et al. Triterpenoids from the Schisandraceae family. Natural product reports. 2008 Oct;25(5):871-91. [Content Brief]

[3]. Zou J, et al. Cycloartane triterpenoids from the stems of Schisandra glaucescens and their bioactivity. Fitoterapia. 2012 Jul;83(5):926-31.

[4]. Lu Y, et al. Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens. Pharmaceutical biology. 2013 Sep;51(9):1204-7. [Content Brief]

[5]. Shu L, et al. Rapid identification of chemical compositions of three species of Schisandra chinensis by ultra-high-performance liquid chromatography quadrupole-orbitrap-mass spectrometry. Journal of separation science. 2023 Oct;46(20):e2300466.

[6]. He F, et al. Nortriterpene constituents from Schisandra sphenanthera. Tetrahedron. 2012 Jan 14;68(2):440-6.

[7]. Li RT, et al. Micranoic acids A and B: two new octanortriterpenoids from Schisandra micrantha. Chemical & pharmaceutical bulletin. 2003 Oct;51(10):1174-6.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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