1. GPCR/G Protein MAPK/ERK Pathway Apoptosis Autophagy
  2. Ras Apoptosis Autophagy
  3. (-)-Rasfonin

(-)-Rasfonin is a fungal secondary metabolite and inhibits small G proteins Ras. (-)-Rasfonin induces apoptosis, necrosis and autophagy in ACHN cells (a renal carcinoma cell line).

For research use only. We do not sell to patients.

(-)-Rasfonin Chemical Structure

(-)-Rasfonin Chemical Structure

CAS No. : 303156-68-5

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Description

(-)-Rasfonin is a fungal secondary metabolite and inhibits small G proteins Ras. (-)-Rasfonin induces apoptosis, necrosis and autophagy in ACHN cells (a renal carcinoma cell line)[1].

Molecular Weight

434.57

Formula

C25H38O6

CAS No.
SMILES

O=C(O[C@H](C=C1)[C@@H]([C@@H](C)C[C@@H](C)C/C(C)=C/C)OC1=O)/C=C/C(C)=C/[C@@H](CO)CCO

Structure Classification
Initial Source

Talaromyces sp. 3656-A1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(-)-Rasfonin
Cat. No.:
HY-121532
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