mTOR inhibitor-18
mTOR inhibitor-18 (Example 106) is a mTOR inhibitor. mTOR inhibitor-18 can be used for mTOR related research, such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
For research use only. We do not sell to patients.
- CAS No.: 2170358-67-3
- Formula: C22H21N7OS
- Molecular Weight:431.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| Dose (mg/kg) | Cmax (μg/mL) | AUC0-t (μg·h/mL) | t1/2 (h) | CL (L/h/kg) | F% |
| IV (5 mg/kg) | 21.2 | 41.455 | 1.416 | 0.122 | |
| PO (10 mg/kg) | 9.987 | 73.44 | 3.258 | 0.247 | 89 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2170358-67-3
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Molecular Weight 431.51
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Formula C22H21N7OS
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SMILES
S=C(NC1=CC=C(C2=NN3C=CC=C3C(N4CCOCC4)=N2)C=C1)NC5=CC=CN=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)