YZ129

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Based on 1 Customer Validation

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration.

For research use only. We do not sell to patients.

  • Purity: 99.85%
  • CAS No.: 1643120-60-8
  • Formula: C19H12N2O2
  • Molecular Weight:300.31
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
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100 mg

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