Ditiocarb
Based on 4 publication(s) in Google Scholar
Ditiocarb (Diethyldithiocarbamic acid) is an accelerator of the rate of copper cementation. Ditiocarb (Diethyldithiocarbamic acid) reduces the incidence of HIV infection, and also enhances adjuvant immunoresearch of high risk breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 147-84-2
- Formula: C5H11NS2
- Molecular Weight:149.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ditiocarb
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CEM-SS | IC50 |
>100 μM
Compound: dithiocarbamate
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Antiviral activity against HIV-1 in CEM-SS cells using XXT assay
Antiviral activity against HIV-1 in CEM-SS cells using XXT assay
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[PMID: 9207937] |
| CEM-SS | IC50 |
>100 μM
Compound: dithiocarbamate
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Antiviral activity against HIV-1ADA in CEM-SS cells using monocyte/macrophage cultures
Antiviral activity against HIV-1ADA in CEM-SS cells using monocyte/macrophage cultures
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[PMID: 9207937] |
Ditiocarb reacts with the Cu2+ solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation[1]. Ditiocarb is an agent with strong antioxidant capacity and chelating activities[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In that AIDS model, Ditiocarb reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 147-84-2
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Molecular Weight 149.28
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Formula C5H11NS2
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SMILES
SC(N(CC)CC)=S
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Synonyms
Diethyldithiocarbamic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
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Journal Impact Factor
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Most Recent
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J Exp Clin Cancer Res
Ferroptosis inducers enhanced cuproptosis induced by copper ionophores in primary liver cancer. [Abstract]2023 Jun 6;42(1):142. PMID: 37277863 -
J Hazard Mater
Stereostructure-activity mechanism of cyproconazole by cytochrome P450 in rat liver microsomes: A combined experimental and computational study. [Abstract]2021 Aug 15:416:125764. PMID: 33827004 -
J Agric Food Chem
Enantioselective Metabolic Mechanism and Metabolism Pathway of Pydiflumetofen in Rat Liver Microsomes: In Vitro and In Silico Study. [Abstract]2022 Mar 2;70(8):2520-2528. PMID: 35184556 -
Pest Manag Sci
The native rice leaf folder can enhance rice resistance against the invasive fall armyworm by inducing the jasmonate-mediated tryptophan metabolism pathway. [Abstract]2026 May;82(5):5026-5039. PMID: 41635108
Purity & Documentation
References
[2]. Hersh EM, et al. Ditiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. A randomized, double-blind, placebo-controlled, multicenter study. JAMA. 1991 Mar 27;265(12):1538-44. [Content Brief]
[3]. Dufour P, et al. Sodium dithiocarb as adjuvant immunotherapy for high risk breast cancer: a randomized study. Biotherapy. 1993;6(1):9-12. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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