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Cat. No.: HY-121357

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Lefucoxib

Lefucoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Lefucoxib can be used in the research of diseases such as osteoarthritis and rheumatoid arthritis.

For research use only. We do not sell to patients.

CAS No.: 849048-84-6
Formula: C₁₉H₁₇F₃N₂O₂S
Molecular Weight:394.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Lefucoxib Chemical Structure

CAS No.: 849048-84-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Lefucoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Lefucoxib can be used in the research of diseases such as osteoarthritis and rheumatoid arthritis^[1].

IC₅₀ & Target^[1]

COX-2

All COX Isoforms :

Chemical Information

CAS No. 849048-84-6
Molecular Weight 394.41
Formula C₁₉H₁₇F₃N₂O₂S
SMILES

CC1=CC=C(C=C1C)C2=CC(C(F)(F)F)=NN2C3=CC=C(C=C3)S(=O)(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bi X, et al. In vivo and in vitro metabolism of lefucoxib in rats. J Pharm Biomed Anal. 2008 Sep 10;48(1):134-9. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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