NO-IN-1
NO-IN-1 (Compound 7a) inhibits the production of NO (IC50 = 3.13 μΜ). NO-IN-1 has anti-inflammatory effects. NO-IN-1 downregulates the expression of COX-2 and iNOS by inhibiting the NF-κB signaling pathway.
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- 分子式: C33H40N4O5
- 分子量:572.69
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
3.13 μM
Compound: 7a
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Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as inhibition of NO production pretreated for 1 hr followed by LPS stimulation and measured after 23 hrs by Griess method
Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as inhibition of NO production pretreated for 1 hr followed by LPS stimulation and measured after 23 hrs by Griess method
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[PMID: 39140047] |
化学情報
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分子量 572.69
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分子式 C33H40N4O5
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SMILES
O=C(OCC1=CN(CCN2C(C(C3=C2C=CC=C3)=O)=O)N=N1)C/C(C=O)=C\C[C@H]4C(CC[C@@]5([H])C(C)(C)CCC[C@]45C)=C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NO-IN-1 関連分類
HY-163888 関連分類
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