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Cat. No.: HY-187060

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Notoptetherin D

Name: Notoptetherin D
Brand: MedChemExpress
SKU: HY-187060
Price: 235.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Notoptetherin D is a coumarin compound isolated from the roots and rhizomes of Notopterygium incisum. Notoptetherin D inhibits nitric oxide (NO) production in LPS (HY-D1056A1)-induced RAW 264.7 cells, with an IC₅₀ of 20.4 μM. Notoptetherin D suppresses nitric oxide generation.

For research use only. We do not sell to patients.

CAS No.: 2899245-61-3
Formula: C₂₃H₂₆O₅
Molecular Weight:382.45

Storage:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Notoptetherin D Chemical Structure

CAS No.: 2899245-61-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

All NO Synthase Isoforms :

In Vitro

Innate Immunity

Notoptetherin D (compound 4) inhibits LPS-induced nitric oxide production in RAW 264.7 cells with an IC₅₀ of 20.4 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2899245-61-3
Appearance Solid
Molecular Weight 382.45
Formula C₂₃H₂₆O₅
Color Off-white to light yellow
SMILES

CCOC(C)(C)/C=C/C/C(C)=C/COC1=C(C=CO2)C2=CC(O3)=C1C=CC3=O
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zheng X, et al. Nitric oxide inhibitory coumarins from the roots and rhizomes of Notopterygium incisum. Fitoterapia. 2018 Nov;131:65-72. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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