D228
Based on 1 Customer Validation
D228 is an orally active antiinflammatory agent. D228 reduces ConA induced T lymphocyte cell proliferation (IC50: 42.85 μM) and LPS induced B lymphocyte cell proliferation (IC50: 3.15 μM). D228 is effective against inflammatory bowel disease (IBD). D228 alleviates the DSS (HY-116282C)-induced inflammation response in the IBD model by downregulating the MyD88/TRAF6/p38 signaling.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 2676188-98-8
- Formula: C22H28O12
- Molecular Weight:484.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2676188-98-8
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Appearance Solid
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Molecular Weight 484.45
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Formula C22H28O12
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Color White to off-white
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SMILES
CC1=C(C(/C(O1)=C(C)\C)=O)O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (103.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0642 mL | 10.3210 mL | 20.6420 mL | 51.6049 mL |
| 5 mM | 0.4128 mL | 2.0642 mL | 4.1284 mL | 10.3210 mL | |
| 10 mM | 0.2064 mL | 1.0321 mL | 2.0642 mL | 5.1605 mL | |
| 15 mM | 0.1376 mL | 0.6881 mL | 1.3761 mL | 3.4403 mL | |
| 20 mM | 0.1032 mL | 0.5160 mL | 1.0321 mL | 2.5802 mL | |
| 25 mM | 0.0826 mL | 0.4128 mL | 0.8257 mL | 2.0642 mL | |
| 30 mM | 0.0688 mL | 0.3440 mL | 0.6881 mL | 1.7202 mL | |
| 40 mM | 0.0516 mL | 0.2580 mL | 0.5160 mL | 1.2901 mL | |
| 50 mM | 0.0413 mL | 0.2064 mL | 0.4128 mL | 1.0321 mL | |
| 60 mM | 0.0344 mL | 0.1720 mL | 0.3440 mL | 0.8601 mL | |
| 80 mM | 0.0258 mL | 0.1290 mL | 0.2580 mL | 0.6451 mL | |
| 100 mM | 0.0206 mL | 0.1032 mL | 0.2064 mL | 0.5160 mL |
D228 Related Classifications
HY-164670 Related Classifications
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