1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. ODN 24991

ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR3, TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. ODN 24991 disrupts TLR3-, TLR7- and TLR9-mediated immune cell immune responses. ODN 24991 sequence: 5'-C-C-T-G-G-C-c7rGm-G-G-G-3'.

For research use only. We do not sell to patients.

DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)

ODN 24991 Chemical Structure

CAS No. : 1682661-49-9

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Based on 1 publication(s) in Google Scholar

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Description

ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR3, TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. ODN 24991 disrupts TLR3-, TLR7- and TLR9-mediated immune cell immune responses. ODN 24991 sequence: 5'-C-C-T-G-G-C-c7rGm-G-G-G-3'[1].

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)

SMILES

[DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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Purity & Documentation

Purity: ≥96.0%

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ODN 24991 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ODN 24991
Cat. No.:
HY-150746
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