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Cat. No.: HY-109841

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Oleoyl serotonin

Name: Oleoyl serotonin
Brand: MedChemExpress
SKU: HY-109841
Price: 115.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Oleoyl Serotonin (compound 1e) is a TRPV1 antagonist with IC₅₀ value of 2.57 μM for human TRPV1.

For research use only. We do not sell to patients.

Purity : 98.28%
CAS No.: 1002100-44-8
Formula: C₂₈H₄₄N₂O₂
Molecular Weight:440.66

Storage:

Solution, -20°C, 2 years

Oleoyl serotonin Chemical Structure

CAS No.: 1002100-44-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Oleoyl Serotonin (compound 1e) is a TRPV1 antagonist with IC₅₀ value of 2.57 μM for human TRPV1^[1].

All TRP Channel Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	2.57 μM Compound: 1e	Antagonist activity at human recombinant TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular calcium elevation Antagonist activity at human recombinant TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular calcium elevation	[PMID: 18027904]

Chemical Information

CAS No. 1002100-44-8
Appearance Liquid
Molecular Weight 440.66
Formula C₂₈H₄₄N₂O₂
Color Colorless to light yellow
SMILES

CCCCCCCC/C=C\CCCCCCCC(NCCC1=CNC2=C1C=C(O)C=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ortar G, et al. New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. J Med Chem. 2007 Dec 27;50(26):6554-69. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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