- Oligonucleotides
- Phosphoramidites
Phosphoramidites
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Phosphoramidites (634)
- Formula: C41H49N4O9P
- Molecular Weight: 772.82
S-cEt-U phosphoramidite is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis.
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- Formula: C47H64N7O7PSi
- Molecular Weight: 898.11
N6-Me-rA Phosphoramidite is a TBDMS-protected nucleoside phosphoramidite, which can be used to create oligonucleotides.
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- Formula: C39H46FN4O8P
- Molecular Weight: 748.78
2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.
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- Formula: C36H39N5O8
- Molecular Weight: 669.72
5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.
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- Formula: C39H37N5O7
- Molecular Weight: 687.74
DMT-OMe-rA(Bz) is a nucleoside analog.
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- Formula: C33H35N3O8
- Molecular Weight: 601.65
DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides.
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- Formula: C48H53FN7O7P
- Molecular Weight: 889.95
DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C52H64N5O10P
- Molecular Weight: 950.07
DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C40H47N4O9P
- Molecular Weight: 758.80
DMTr-LNA-U-3-CED-phosphora is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- Formula: C33H43N2O5P
- Molecular Weight: 578.68
Spacer phosphoramidite C3 is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- Formula: C50H57N6O9P
- Molecular Weight: 917.00
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- Formula: C53H66N7O8PSi
- Molecular Weight: 988.19
3'-TBDMS-Bz-rA Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- Formula: C43H55N4O10P
- Molecular Weight: 818.89
2'-O-MOE-5MeU-3'-phosphoramidite is a phosphoramidite derivative that can be used for oligonucleotide synthesis.
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- Formula: C48H54N7O8P
- Molecular Weight: 887.96
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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- Formula: C51H53ClN7O7P
- Molecular Weight: 942.44
Activated DPG Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy.
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- Formula: C37H37ClN5O5P
- Molecular Weight: 698.15
Activated C Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy.
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- Formula: C47H54N5O9P
- Molecular Weight: 863.93
3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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- Formula: C40H49N4O9P
- Molecular Weight: 760.81
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- Formula: C45H56N7O9P
- Molecular Weight: 869.94
3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
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- Formula: C50H68N7O9PSi
- Molecular Weight: 970.18
I-bu-rG Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of nucleotides and nucleic acids.
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