Parawixin10
Parawixin10 (Compound 2) is an N-acylpolyamine. Parawixin10 fails to enhance glutamate uptake in radioligand uptake assays of EAAT1, EAAT2 or EAAT3. Parawixin10 exhibits no positive allosteric modulatory activity in radioligand uptake assays of EAAT1−EAAT3, nor can it improve neuronal survival rates in mice in a dose-dependent and statistically significant manner. Parawixin10 has no neuroprotective activity.
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- Fòrmula: C30H55I2N9O3
- Peso molecular:843.63
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
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EAAT1 |
EAAT2 |
EAAT3 |
In Vitro
Chemical Information
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Peso molecular 843.63
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Fòrmula C30H55I2N9O3
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SMILES
C[N+](C)(CCCC[N+](C)(C)CCCNC(CC1=CNC2=CC=CC(O)=C21)=O)CCCNC([C@H](CCCNC(N)=N)N)=O.[I-].[I-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Doroudian Y, et al. The N-Acylpolyamine Structure Assigned as Parawixin10 Does Not Display Positive Allosteric Modulatory Activity in EAAT1-3 Radioligand Uptake Assays, nor Does It Enhance Neuronal Survival in Mice in a Dose-Dependent and Statistically Significant Way. ACS Chem Neurosci. 2026;17(8):1530-1539. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Parawixin10 Related Classifications
HY-182941 Related Classifications
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