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Cat. No.: HY-132887

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PDE4-IN-3

PDE4-IN-3 is a novel and orally active PDE4 inhibitor with potent inhibitory affinity (IC₅₀ = 4.2 nM).

For research use only. We do not sell to patients.

CAS No.: 2755687-49-9
Formula: C₃₅H₃₃FO₈
Molecular Weight:600.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PDE4-IN-3 Chemical Structure

CAS No.: 2755687-49-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PDE4-IN-3 is a novel and orally active PDE4 inhibitor with potent inhibitory affinity (IC₅₀ = 4.2 nM).

All Phosphodiesterase (PDE) Isoforms :

Chemical Information

CAS No. 2755687-49-9
Molecular Weight 600.63
Formula C₃₅H₃₃FO₈
SMILES

O=C1C2=C(OC3=CC(OCC4=CC=C(C=C4)F)=C(C(C/C=C(C)\C)=C31)OC)C=C5OC(C)(C=CC5=C2OC/C=C/C(O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huang YY, et al. Mangostanin Derivatives as Novel and Orally Active Phosphodiesterase 4 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety. J Med Chem. 2021 Sep 23;64(18):13736-13751. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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PDE4-IN-3

All Phosphodiesterase (PDE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PDE4-IN-3 Related Classifications

HY-132887 Related Classifications