PqsR/LasR-IN-2
Based on 1 Customer Validation
PqsR/LasR-IN-2 (Compound 3) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-2 also inhibits hERG with the IC50 of 1.408 µM.
For research use only. We do not sell to patients.
- CAS No.: 2071705-93-4
- Formula: C21H23ClN4O2
- Molecular Weight:398.89
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Antibiotic Isoforms
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Biological Activity
Chemical Information
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CAS No. 2071705-93-4
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Appearance Solid
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Molecular Weight 398.89
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Formula C21H23ClN4O2
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Color Off-white to light yellow
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SMILES
CCC(C1=CC=C(C=C1)OCCOC2=CC=C(C=C2/C=N/N3C=NN=C3)Cl)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (250.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5070 mL | 12.5348 mL | 25.0696 mL | 62.6739 mL |
| 5 mM | 0.5014 mL | 2.5070 mL | 5.0139 mL | 12.5348 mL | |
| 10 mM | 0.2507 mL | 1.2535 mL | 2.5070 mL | 6.2674 mL | |
| 15 mM | 0.1671 mL | 0.8357 mL | 1.6713 mL | 4.1783 mL | |
| 20 mM | 0.1253 mL | 0.6267 mL | 1.2535 mL | 3.1337 mL | |
| 25 mM | 0.1003 mL | 0.5014 mL | 1.0028 mL | 2.5070 mL | |
| 30 mM | 0.0836 mL | 0.4178 mL | 0.8357 mL | 2.0891 mL | |
| 40 mM | 0.0627 mL | 0.3134 mL | 0.6267 mL | 1.5668 mL | |
| 50 mM | 0.0501 mL | 0.2507 mL | 0.5014 mL | 1.2535 mL | |
| 60 mM | 0.0418 mL | 0.2089 mL | 0.4178 mL | 1.0446 mL | |
| 80 mM | 0.0313 mL | 0.1567 mL | 0.3134 mL | 0.7834 mL | |
| 100 mM | 0.0251 mL | 0.1253 mL | 0.2507 mL | 0.6267 mL |