PROTAC ERα Degrader-6 

PROTAC ERα Degrader-6 (compound A3) is a potent PROTAC degrader of ERα, with DC₅₀ of 0.12 μM. PROTAC ERα Degrader-6 has anti-tumor effect. PROTAC ERα Degrader-6 is a fluorescent probes with Em of 582 nm that enable real-time visualization of ERα protein degradation^[1].

PROTAC ERα Degrader-6 (compound A3) displays exceptional anti-proliferative activity against MCF-7 cells (IC₅₀=0.051 μM)^[1].
PROTAC ERα Degrader-6 exhibits exceptional fluorescence imaging performance with λ = 582 nm, a Stokes shift of 116 nm^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

913.09

C₅₁H₅₆N₆O₈S

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Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Xiaohua Wang, et al. Fluorescence theranostic PROTACs for real-time visualization of ERα degradation. Eur J Med Chem. 2024 Feb 1:267:116184.  [Content Brief]