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Cat. No.: HY-169276

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PROTAC SMARCA2 degrader-25

PROTAC SMARCA2 degrader-25 (example 86) is a potent PROTAC SMARCA2 degrader with the DC₅₀ of ＜0.01 μM.
(Pink: SMARCA2 ligand (HY-169487); Blue: Cereblon ligand (HY-W087383); Black: linker).

For research use only. We do not sell to patients.

CAS No.: 2770571-17-8
Formula: C₃₈H₄₁N₉O₆
Molecular Weight:719.79

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PROTAC SMARCA2 degrader-25 Chemical Structure

CAS No.: 2770571-17-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PROTAC SMARCA2 degrader-25 (example 86) is a potent PROTAC SMARCA2 degrader with the DC₅₀ of ＜0.01 μM^[1]. (Pink: SMARCA2 ligand (HY-169487); Blue: Cereblon ligand (HY-W087383); Black: linker).

All PROTACs Isoforms :

Chemical Information

CAS No. 2770571-17-8
Molecular Weight 719.79
Formula C₃₈H₄₁N₉O₆
SMILES

O=C1CCC(C(N1)=O)N2C(C3=C(C2=O)C=C(C=C3)N4CC(C4)CN5CCC(CC5)C(N6CCN7C8=C(NC[C@H]7C6)N=NC(C9=C(C=CC=C9)O)=C8)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Prelude Therapeutics Incorporated. BRM targeting compounds and associated methods of use. World Intellectual Property Organization, WO2022099117 A1 2022-05-12

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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PROTAC SMARCA2 degrader-25

All PROTACs Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PROTAC SMARCA2 degrader-25 Related Classifications

HY-169276 Related Classifications