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Cat. No.: HY-121944R

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Ricinine (Standard)

Ricinine (Standard) is the analytical standard of Ricinine (HY-121944). This product is intended for research and analytical applications. Ricinine is a central nervous system stimulant found in Ricinus communis. Ricinine binds near the benzodiazepine site of the GABA_A receptor, reducing benzodiazepine binding affinity through an allosteric effect, and shows no interaction with AMPA, 5-HT_1A, muscarinic receptors, or α₁ adrenergic receptors. Ricinine improves memory consolidation in mice at low doses, while at high doses it induces seizures, an effect that is selectively inhibited by diazepam. Ricinine shortens the lifespan of Anopheles mosquitoes through sugar feeding and promotes the development of Plasmodium falciparum in mosquitoes. Ricinine is used in research related to epilepsy, amnesia, and malaria.

For research use only. We do not sell to patients.

CAS No.: 524-40-3
Formula: C₈H₈N₂O₂
Molecular Weight:164.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ricinine (Standard) Chemical Structure

CAS No.: 524-40-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-121944
Ricinine

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- Application
Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 524-40-3
Molecular Weight 164.16
Formula C₈H₈N₂O₂
SMILES

N#CC1=C(OC)C=CN(C)C1=O
Structure Classification
- Alkaloids
- Pyridine Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Ferraz AC, et al. Ricinine-elicited seizures. A novel chemical model of convulsive seizures. Pharmacology, biochemistry, and behavior. 2000 Apr;65(4):577-83.

[2]. Ferraz AC, et al. Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis. Pharmacology, biochemistry, and behavior. 1999 Jul;63(3):367-75.

[3]. Hien DFDS, et al. Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum. Parasites & vectors. 2021 Sep 15;14(1):479. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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