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Cat. No.: HY-W295201

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ROCK-IN-11

ROCK-IN-11 (example 94) is a potent inhibitor of ROCK1 and ROCK2, with the IC₅₀ of ≤ 5μM. ROCK-IN-11 plays an important role in cancer research.

For research use only. We do not sell to patients.

CAS No.: 445267-51-6
Formula: C₂₂H₂₀N₄O₄S
Molecular Weight:436.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

ROCK-IN-11 Chemical Structure

CAS No.: 445267-51-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ROCK-IN-11 (example 94) is a potent inhibitor of ROCK1 and ROCK2, with the IC₅₀ of ≤ 5μM. ROCK-IN-11 plays an important role in cancer research^[1].

All ROCK Isoforms :

Chemical Information

CAS No. 445267-51-6
Molecular Weight 436.48
Formula C₂₂H₂₀N₄O₄S
SMILES

COC1=C(C(=CC(=C1)NC(=O)C2=C(C3=C(N=C(C=C3)C4=CC=NC=C4)S2)N)OC)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mehmet Kahraman, et al. Benzothiophene derivatives, processes for preparing them, pharmaceutical compositions containing them, and their use as inhibitors of Rho kinase. World Intellectual Property Organization, WO2008011560 A2 2008-01-24

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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ROCK-IN-11

All ROCK Isoforms