Schisandrol B (Standard)
Schisandrol B (Standard) is the analytical standard of Schisandrol B. This product is intended for research and analytical applications. Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities.
For research use only. We do not sell to patients.
- CAS No.: 58546-54-6
- Formula: C23H28O7
- Molecular Weight:416.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 58546-54-6
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Molecular Weight 416.46
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Formula C23H28O7
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SMILES
O[C@@]([C@@H](C)C1)(C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3OC
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Synonyms
Gomisin-A (Standard); TJN-101 (Standard); Wuweizi alcohol-B (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jiang Y, et al. Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. Toxicol Sci. 2015 Jan;143(1):107-15. [Content Brief]
[2]. Jeong-Seok Kim, et al. Gomisin A modulates aging progress via mitochondrial biogenesis in human diploid fibroblast cells. Clin Exp Pharmacol Physiol. 2018 Jun;45(6):547-555. [Content Brief]
[3]. Jin J, et al. Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats. Biopharm Drug Dispos. 2010 May;31(4):264-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Schisandrol B (Standard)
- 58546-54-6
- Gomisin-A (Standard)
- TJN-101 (Standard)
- Wuweizi alcohol-B (Standard)
- Reference Standards
- Reactive Oxygen Species (ROS)
- Cytochrome P450
- Autophagy
- Hepato-protective
- CYP2E1
- CYP3A11
- p53
- p21
- CCND1
- PCNA
- BCL-2
- lignan
- P-glycoprotein
- anti-inflammatory
- anti-diabetic
- antioxidant
- Inhibitor
- inhibitor
- inhibit